Focus on the hometown of amazon, Boeing, CRAY, Microsoft, Bill & Melinda Gates foundation, et al Fortunete! Where else can creative work smarter, play harder?! What can reenergize them for new projects better than rendezvous with Mt. Rainier, Olympic Rainforest and Cape Flattery? Only an electrifying ablution in Lake Diablo after climbing the Forbidden Peak of American Alps, flying Unlimited under Blue Angels exiting Nesterov loops atop the richest's estate, Blackcomb double black diamond running followed with the San Juan Islands sailing, and deeply relaxing Washington wineries touring plus dopamine-releasing 1812 Overture at Benaroya Hall!
To us as biomedical scientists, the most addictive local attraction was the unique intellectual atmosphere of the America's brainiest city homing the most innovative public university, UW, Institute for Systems Biology, Allen Institutes for Brain, Artificial Intelligence and Cell Sciences, Fred Hutchinson Cancer Research Center, and other top-notch biomedical research organizations fighting immunodeficiency, diabetes, obesity, cardio-vascular and other humanity-most-devastating diseases. So, we joined UW Medicine and Pacific NW Research Institute to power our studies of normal vs pathogenic mutant ABCC8(9)/KCNJ11(8)-coded ATP/ADP-sensitive K+ channels, KATP, and then started up Babenko Lab for Molecular Electrophysiology, Biopysics & Pharmacology. As many remember, Babenko et al were first to record KATP in human cardiocytes, relate structure to function in the myo vs neuroendocrine 'metabolic sensors', identify (SURx/Kir6.x)4 mutants causing diabetes, seizures, developmental et alii morbi, and rescue their carriers with sulfonylurea receptor isoform-specific modulators. Today, we aim to decipher how these amazing heteromers and related membrane transport proteins function in differentiated, 'stem' (Maksimov) and hyperproliferating cells, and translate the know-how into innovative precision therapies. We seek a sponsor/institution strong/wise enough to let us pursue Xtreme Life $cience ‒ even capturing Å-resolution movies of our membrane lipids- and other ligands-controlled transchænzines™ at the fastest, hardest and most brilliant XFEL ‒ for the best of humanity.
To imagine how we work and play in and around the sleepless city take Starbucks caffeine quantum satis and