Focus on the homeplace of amazon, Boeing, CRAY, Microsoft, Bill & Melinda Gates Foundation, et al Fortunete! Where else can creative work smarter, play harder?! What can energize pathbreakers and explorers fuller than rendez-vous with Mt. Rainier, Olympic Rainforest and Cape Flattery? Perhaps electrifying ablutions in Lk. Diablo after climbing the Forbidden Peak of American Alps, flying Unlimited under Blue Angels drawing Nesterov loops above Premier Properties, Blackcomb double-black-diamond running followed with San Juan Islands sailing, and Wonderful Washington Wineries touring après our dopamine-releasing 1812 Overture at Benaroya Hall!
To us, biomedical scientists, the most addictive Pacific NW's αttraction is the unique intellectual atmosphere of the America's brainiest city, homing the most innovative public university, UW, Institute for Systems Biology, Allen Institutes for Brain, Artificial Intelligence and Cell Sciences, Fred Hutchinson Cancer Research Center, and other top-notch biomedical research organizations fighting immunodeficiency, diabetes, obesity, cardio-vascular and other humanity-most-devastating diseases. We first joined UW Medicine and Pacific NW Research Institute to power our studies of normal vs pathogenic mutant ABCC8,9/KCNJ8,11-coded, ATP/ADP-sensing K+ channels, KATP, and then started up Babenko Lab for Molecular Electrophysiology, Biophysics & Pharmacology. As many likely know, Babenko et al were first to record KATP in human cardiocytes, relate structure to function in the myo- vs neuro-endocrine metabolic sensors, identify (SURx/Kir6.x)4 mutants causing diabetes, seizures, developmental et aliis morbis, and rescue their carriers by sulfonylurea receptor isoform-specific modulators. Now we must decipher how the most complex "biodiodes" and related membrane transport proteins function in differentiated, "stem" [Maksimov] and hyperproliferating cells, and translate our know-hows into innovative precision therapies. We seek α sponsor organization strong and wise enough to let us pursue EXTREME LIFE SCIENCES' objectives ‒ even capturing Å-resolution movies of our membrane lipids- and smaller ligands-gated transchænzimes™ at the fastest, hardest and brilliantest X-ray Free Electron Laser ‒ for the benefit of mankind.
To imagine how we work and play in and around the sleepless city, take Starbucks caffeine quantum satis and