SUR/KIR6 and Disorders of Metabolism-Excitation Coupling
Here are some images of the Babenko Lab at the Pacific NW Research Institute. Check out our "arsenal".
This electrophysiological setup was used to characterize pancreatic beta-cells from SUR1-null mice
This patch-clamp setup is used for single-channel recording and analysis of stochastic transitions that gate ion channels. It includes a fluorescence module to visualize tagged subunits, and a rapid solution changer to determine ligand doze-responses. All the devices are controlled via PCs communicating with the server. Many parts of this setup were custom made. We thank Russian Foundation for Fundamental Investigations, INSERM, American Heart Association, and NIH for their support, making possible to obtain numerous pieces of equipment for this setup.
The entrance to "The Dark Space", where we build our new advanced microscopy system
This is our shared Leica DM6000B/CTR7000-based Ca2+ microfluorometry setup.
this fast Real Time PCR System from ABI, StepOnePlus. We also share
these ABI Prism 310 Genetic Analyzers, this Packard COBRA II Auto Gamma Counter,
this Beckman LS 6500 Multi-purpose Scintillation Counter,
this Perkin Elmer Wallac Victor2 1420 Multilabel Counter,
this HORIBA Fluorolog spectrophotometer,
this complete Warner Planar Lipid Bilayer Workstation,
and this Bio-Rad Gene Pulser II Electroporation System.
the common area with this ELGA Purelab/Barnstead NANOpure Infinity water purification combo,
several ultra low temperature freezers and refrigerators, as well as
these Sorvall RC M120CX/Evolution and Beckman J2-HS/J-6M/TL-100?Optima XL-80K ultracentrifuges.
We have free access to other general laboratory equipment and instruments around, including
this Savant Speed Vac Plus SC110A/Novalyphe-NL150 vacuum pump system,
these Bio-Rad 583 Gel Dryers,
this FOTODYNE Foto/Analyst 'Investigator' with 60-2030 Coomassie Blue and 60-2031 Ethidium Bromide Filters,
this EG&G Berthold Lumam LB9507,
this New Brunswick BioFlo/CelliGen 115,
and this Pharmacia FPLC System.
Moreover, adjacent to the Babenko Lab space on the fourth floor, there are
this commonly used Ice-O-Matic machine from Welbilt Company and
this cold room, well equipped for a protein biochemistry work.
Finally, here the PI is reviewing, modeling, designing, writing, submitting... screaming, rebuttling, loosing hope, and, after all, finding solutions -- to celebrate this life just a few times a year by opening his narrow office window... ...and enjoying that wide perspective!
In this warmer room, our research scientists can analyze and discuss data which they collected.


