Curricula Vitae, Résumés and Biodata with  Contemporary Memoirs 'Жизненные Истории'

"Народ, не знающий своего прошлого, не имеет будущего." [People ignorant of their past have no future] -

Михаил Васильевич Ломоносов [Mikhail Vasilyevich Lomonosov]


"Le bon Dieu est dans le détail" [The good God is in the detail-

Gustave Flaubert


изнь - товар на вынос:                         [How you present your                      "C'est la vie - you're selling

торса, пениса, лба.                                    torso, phallos, thoughts                   Torso, stamina, and brain.

плюс биографии примесь –                        and biography records                      With your biography swelling,

получилась судьба."  -                              determines your fate.]                      Show your CV - climb again!"

 

Иосиф Алексaндрович Бродский

[Joseph Aleksandrovich Brodsky],             translated    prosaically,       and       as   a   poetic   epigraph   by




not related to Prince Andrey Petrovich or any Babenko on

EDUCATION

B.S./M.Sc. in Physics/Radiophysics from Alma Mater of numerous Nobelists in every Field, Saint Petersburg State University, where Mendeleev, Popov, Markov et al Chemists, Physicists, Mathematicians, other Scientists, Literators and Statesmen have achieved breakthroughs changing the world. There, the 'A'-Student Babenko has underachieved 'B' in Statistical Thermodynamics and Nonlinear Acoustics after colliding with Илона М. Смагаринская walking like dancing on Italian hills in the subsequently presidentially-tramped SPbSU Runway  and spending his energy on bonding with that Красавица (Rare Beauty, see below) rather than on exciting his examiners presiding on the top floor of the top Faculty of Radiophysics in the Universe. But after producing with her the next generation Krasavitsa (see later), the Gen X Ανδρέας presented his scientific findings about non-classified effects of non-ionizing radiations, including mm-radio-waves and ultra-short acoustic waves, that he's made while experimenting in a Biophysical Research Lab at the legendary Military Medical Academy (see more about the Organization there) in then Leningrad (notice Responses of Complex Biological Systems to Application of Low-Intensity '"Millimetric" Waves by G. N. Chernyakov, V. L. Korochkin, A. P. Babenko, E. V. Bigday, In: 'Millimetric' Waves in Medicine and Biology. Moscow, 1989, Edited by N. D. Devyatkov, pp. 140-167 [in Russian], A. P. Babenko, G. N. Chernyakov, 1992, in the PubMed accessible journal, and subsequent related Applications and Patents copied not only by Google xeroxcopists here, here, here, here and there), defended his 'A+'-graded Thesis EPR spectroscopy analysis of blood plasma from men in malady (not le malade, but a common disease he conquered later), and graduated with Hex#90000 Magister Diploma G1 N397845 in 1993.

M.D. with egregia cum laude (Crimson Diploma with Gold Medal HB N789251from S. M. Kirov Military Medical (formerly Imperial Medico-Surgical) Academya.k.a. MMA, VMA, VMedA, where the most promising applicants, theyoung not-too-gentle men only, were selected at a <5%-rate by a Scientific Knowledge, Health, Physical & Psychological Strength Examining Federal Commission - not like any of Super-Profiting Western Medical  School Admission Offices auctioning Early Admission tickets for the next generation Western Elite paying for playing under supervision of Secret Servicemen - for a brutal 6-day-a-week-6-year Medical Training Program to learn Physiology and Pharmacology at Sechenov and Pavlov Departments, Biological & Medical Physics at Petrov Department, Diagnostics and Therapy in Botkin Hospital, Topographic Anatomy & Operative Surgery in Pirogov Institute, Pathology at Anichkov Department, Psychiatry and Conditioning (translated as Cognitive Behavior Therapy) in Bekhterev Clinic, Hematology, Immunology and Regeneration in the CIA-loved Arinkin and Maksimov Clinical Research Centers, Parasitology and Epidemiology of Infectious Diseases in then the USSR leading Pavlovsky Institute, and about 50 more Disciplines and Specialties, including Military Virology, Bacteriology, Toxicology, Radiobiology and the world's #1 Space Medicinein elite Institutions for Advanced Biomedical Research. The Medical Cadet Babenko has spent enough time at the Academy Kitchen & Dining Halls to pass the test in gentlemen's favorite Facultative Course Nutrition and Aæthetics of Feeding, taught by a tasteful, CA Instructor). Андрей Петрович codenamed BOA (Boa of σκληπιός) has also spent quite a time at the Academy Training 'Farm' surrounded by swamps, where he, moving аки тать в нощи, with a still classified number of poods of special medical equipment and other tools attached to his camouflaged back-pack, tæsted Vaccinium angustifolium et Artemisia annua (Artemisinin was prized in the West 25+ yrs later) while shooting useless females from the deadliest swamp near Krasnoye Selo with a laser pointer during the White Nights, not under garage lamp lights, as was staged in the next 25+-yeas-lateSDI-funded Intellectual Ventures movie. Upon completion of his Stagerovka (brief Residenture) at the Best Army Base in Beautiful Carelia and the Best Hospital in Hansom Vyborg, the NorthWest Region, the never-filmed, just B&W Photo-documented, Doctor and Officer "AB 008" took his Hippocratic Oath under the prettiest Hygieia and abluted the rarest Academic Romb in the purest Caucasian Borjomi while banqueting with other Golden Boysnone of whom has however received his favorite and the most prestigious Orden, in Granovitaya and Georgievsky Palaces, as both places ran out of Mendeleev-invented antifreeze needed to mix ex tempore w/o shaking the most celebrated binary celebratory drink much more appropriate than just the Aqua from then The Soviet Republic of Georgia discovered by Imperial Russian Military, on the day of The Corrupt Perestroishik, a.k.a. Loser Gorbachev's, Order "No more alcohol in Kremlin", in 1988. [WARNING: Readers of this Memoir, who do not smile at this point should stop doing so or seek a doctor from the MMA's Bekhterev Clinic!]

Ph.D. in Medical Sciences - Biophysics, from VMedA Interdepartmental Laboratory of Cellular Physiology and Biophysics (later the CPB Lab at INFRAN), Russian (then USSR) Academies of Sciences and Medical Sciences (RAS/RAMS), and Ministry of Defence's Medical Department. Dr. Andrey P. Babenko defended his "Principles of Cardiac Potassium Channels' Responses to Stimuli of Certain Physico-Chemical Nature" (Thesis Adviser - Corresponding Member of RAMS, Head of the CPB at Pavlov Institute for Physiology RAS, former Head of the Department of Medical and Biological Physics of VMA and then the Academy's Vice-President for Science and Education, General-Major of Military Medical Service, Honorary Member of the National Naval Medical Center in Bethesda and Wilford Hall Medical Center in San-Antonio in the U.S., the past SPbSTU's Faculty of Medical Physics and Bioengineering Dean, and Chairman of VMedA's Department of Normal Physiology, Professor of Biophysics, Vladimir O. Samoilov) and received his Medical Scientist (Hex#722f37Doctoral Diploma N055286  in 1992, to become the youngest interdisciplinary MS/MD/PhD Scientist plus non-Corporate but Commanding Medical Officer (Военврач in RU) who refused to become a traitor and make money with Doctor of Theology.

 


"What for is this 6+6+4-year advanced education money can't buy in the States were some with just a high school diploma became the richest CEO?" - American Interviewer

"Learning is a treasure that will follow its owner everywhere." - Chinese Proverb

"Only the educated are free." - Ἐπίκτητος [Epictetus]

"Any existing distinction between the wise and the stupid... comes down to a matter of education." - 福澤 諭吉 Fukuzawa Yukichi

"There is a cult of ignorance in the United States, and there has always been. The strain of anti-intellectualism has been a constant thread winding its way through our political and cultural life, nurtured by the false notion that democracy means that "my ignorance is just as good as your knowledge." - Isaac Azimov

"Democracy cannot succeed unless those who express their choice are prepared to choose wisely. The real safeguard of democracy, therefore, is education." - Franklin D. Roosevelt, praised by another wise Statesman

“Modern cynics and skeptics see no harm in paying those to whom they entrust the minds of their children a smaller wage than is paid to those to whom they entrust the care of their plumbing.” - John F. Kennedy, shortly before he was assassinated

"The function of education is to teach one to think intensively and to think critically. Intelligence plus character - that is the goal of true education. Martin Luther King, Jr., shortly before he was assassinated

"Education is the most powerful weapon which you can use to change the world." - Nelson Mandela, a unique black President who changed the world to be a better place for millions of black and yet died naturally

"Focusing your life solely on making a buck shows a poverty of ambition. It asks too little of yourself. And it will leave you unfulfilled." - Barack Obama, an ambitious speech reader, who, after taking the 'Dynamite Man' Peace Pri$e, has enabled I$IL, CIA Drones and U.S. Missiles threatening Russia, Coup d'état in Ukraine, et al Criminal Operation$ of the Military-Industrial-Financial Complex-serving Deep $tate, making a buck from each of them

"What is the purpose of industrial education? To fill the young of the species with knowledge and awaken their intelligence? Nothing could be further from the truth. The aim is simply to reduce as many individuals as possible to the same safe level, to breed and train a standardized citizenry, to put down dissent and originality. That is its aim in the United States..." – Henry Louis Mencken

"Getting a job is not the purpose of school." - Terry Heick

"Education is not preparation for life; education is life itself." - John Dewey

"Once you stop learning you start dying" - Albert Einstein

"Век живи - век учись [Live for a century - learn for a century]" - Russian Proverb


ADVANCED POSTDOCTORAL TRAINING В ЧУЖЕСТРАНЬЕ (IN THEN €-FREE WESTERN EUROPE AND PRE-'IRAQI FREEDOM' U$A)

Upon recommendation of the Full Member of RAMS et al Academia Professor V. A. Tkachuk, who headed the Faculty of Fundamental Medicine at Lomonosov Moscow State University (MSU) plus a few top Institutes for Biomedical Research, Dr. Babenko, M.Sc., M.D., Ph.D. applied for, and won, MESR International Fellowship at the National Institute of Health and Medical Research (INSERM) Unit of Cardiovascular Physiopathology - moving from Paris Sud to Southern France to co-occupy the new research building in Montpellier with the Unit for Studies of Diabetes led by Dr. Bataille then working on endosulfine pepties - under the direction of Member of Academia Europaea's Physiology and Neuroscience Section, Dr. G. Vassort (now Directeur Emeritus). Using a combination of advanced electrophysiological techniques, micro-spectrofluorometry methods, micro-injection, and selective blockers and agonists, Drs. Babenko and Vassort co-investigated Regulation and pharmacological modulation of ATP-sensitive potassium and ATP-gated calcium-permeable cation channels under pathological conditions. The two Med Scientists became colleagues and friends forever remembering these exciting times, in 1995-6, while they were working and playing in the magestic hometown of the oldest Faculty de Medecnie where Physiologistes et Médecins have discovered the hypoglycemic action of KATP-inhibiting sulfonamides, changing for good lives of billions with type 2 Diabetes, without talking much about, and without getting any Prize for, that Contribution to Physiology and Medicine.



Next, in 1996, instead of enjoying tenure at Pavlov First St. Petersburg State Medical University, and INFRAN, Dr. Babenko decided to take the three-year JDRF International Fellowship in the Laboratory of the 1996' DeBakey Prize Nominee, Prof. of Cell Biology J. Bryan at the Baylor College of Medicine's Top Department under "the father of molecular endocrinology", BCM MCB in Houston, TX, to pioneer the primary structure-function analyses of "metabolic sensors", including normal and mutant cardiovascular and neuroendocrine ABCC8,7/KCNJ11,8-coded, [ATP]/[MgADP]-sensing, selectively potassium-conducting, tetra-heterodimeric KATP complexes of inward rectifiers, KIR6.x, and sulfonylurea receptors, SURx, cloned separately by Seino and Bryan groups, and famously reunited [reconstituted by coexpression generating KATP currents, IKATP] by the two teams in Chiba and Houston upon the brilliant suggestion of Daniel Cook, then Professor of Physiology and Biophysics at the University of Washington in Seattle. Working in the America's top Department of the World's Biggest Medical Center's School of Medicine gave Dr. Babenko a super-excitement, a superb satisfaction, and a superior experience in leading a discovery process even in a pseudo-egalitarian atmosphere of an ultra-conservative Private Medical School in the uniformly Red State with a terrible climate.



POSITIONS AND RESEARCH PROGRAMS (IN REVERSE CHRONOLOGICAL ORDER POPULARIZED BY LINKEDID)

Principal Scientist - Head of the Private Nonprofit Research Laboratory for Molecular Electrophysiology, Biophysics and Pharmacology, Principal Investigator, Adjunct Research Professor of Molecular Physiology and Biophysics, affiliated with the former Pacific NorthWest Research Foundation/Diabetes Research Institute and Diabetes Endocrinology Research Center of the University of Washington in Seattle (UW). Since 2009. PI, the NIH Project ABCC8/KCNJ11 Mechanisms and Diabetes, focused on (SURx/Kir6.x)4 in Pathophysiology and Personalized Treatment of Neonatal Diabetes, ND w/ Epilepsy and Developmental delay, DEND Syndrome, Maturity-Onset Diabetes of Young, MODY12 and 13, and Type 2 Diabetes, T2D. Directed the DoD/PNRF/I-sponsored Pilot studies of mutant metabolic sensors altering neuronal excitability. Started Private No-profit Research Initiative International Exploratory Investigations of Rare Orphan Transprtochannelopathies, including Hypertrichotic Osteochondrodysplasia with Cardiomegaly and Hyperproliferative Dysplasias. 2013-


Scientist at Pacific Northwest [once Diabetes] Research Institute - Affiliate Associate Professor of Physiology and Biophysics at the UW Diabetes Endocrinology Research Center. Co-PI, NIH R01 Studies of Sulfonylurea Receptors and KATP Channels. Using patch-clamping, photolabeling,  mutagenesis, and molecular dynamics simulation, established mechanisms of diabetogenic and epileptiformic KATP overactivity, determined the stoichiometry of Mg·nucleotide hyper-stimulation of ND-SUR based channels, and deduced the relative pathogenicity of mixed KATP in subjects with heterozygous mutations in KATP genes, thus answering all three longstanding questions in the field. 2007-9.


Assistant Professor of Molecular and Cellular Biology, Baylor College of Medicine (BCM), Houston, TX. PI, American Heart Association (AHA) National Scientist Development Program on Molecular Pharmacology of Cardiovascular KATP. Co-PI, NIDDK R01 Studies of Sulfonylurea Receptors and ATP-sensitive Potassium Channels. Analyzed structural determinants of gating in (SUR/KIR6)4 isoforms that link the metabolic status and electrical activity of insulin-secreting cells, neurons, striated myocytes and vascular smooth muscle cells. Defined TMD0-L0 of SUR as a "gatekeeper" that links the multi-drug-binding TMD1-NBD1-TMD2-NBD2 core of SUR with the KIR6 pore and bidirectionally controls the open channel probability, PO. Analyzed structure-activity relationships for SU and non-SU inhibitors of KATP variants and defined the bipartite nature of the pocket for these drugs, leading to re-grouping/classifying them as A-, B-, and A/B-site insulinotropes. In collaboration with Prof. P. Froguel and other European Medical Geneticists, discovetred multiple gain-of-PO mutations that cause either Transient or Permanent ND with neurological abnormalities, and successfully switched their carriers from insulin pumps and life-long insulin injections to SUR1-specific sulfonylurea tablets, recommended by the World Health Organization (WHO) as an essential, tier 1, antidiabetic medicine. 2002-7.

 

Instructor of Molecular and Cellular Biology, BCM MCB. PI, AHA Beginning Grant-in-Aid Cytoplasmic Domains of Kir6.2, SUR2A, and Their Interaction in Gating and ATP-inhibition of Human Cardiac KATP. Co-Investigator, NIH R01 Structure of ATP-sensitive Potassium ChannelsRevealed the primary structure-function relationships in KIR6.1-based "KNDP" and KIR6.2-based "classic" KATP, using chimeric ABCCs, hybrid KIRs, their concatemers, synthetic peptides, affinity photo-labeling, and single-channel recording. Delineated the SUR N-terminal part specifying dissimilar intrinsic PO of classic KATP isoforms. Clarified specific functions of cytoplasmic domains of KIR6.1(2) and nucleotide binding domains (NBD) 1 and 2 in nucleotide-binding sites (NBS)1/2 of ABCC8(9) in gating of KATP variants. Established effects of KIR6 subunit composition and order on the conductivity and gating of hetero-octameric channels. Found 'hybrid' KATP in developing cardiomyocytes; defined pharmaco-topology of SUR1 and SUR2 variants. Identified the SU-binding locus and domains that recognize K+ channel openers. All that was achieved in 1999-2002 while Dr. Babenko was "trapped" in the transition state of Instructor, opposing the BCM Executives-supported Militaristic Bushism.


Senior Fellow of the Juvenile Diabetes Research Foundation International in Joseph Bryan Lab at BCM MCB, while on a long-term sabbatical from Pavlov First State Medical University and Institute of Physiology of RAS. Pioneered JDRF/NIH-funded Analyzes of structure vs activity in cloned pancreatic and extra-pancreatic KATP, using electrophysiological, biophysical and molecular biology methods. Originally reconstituted and fully characterized human sarcolemmal KATP (hu-sarco-KATP). Showed the role of regulatory SUR subunits in trafficking, spontaneous single-channel bursting, and nucleotide regulation of all KIR6-based channels. Using innovative chimeric human ABCCs, engineered without introducing amino acid mutations, led the Glaxo Smith Kline-sponsored Analysis of functional pharmacotopology of human SUR1 vs SUR2 isoforms. 1996-9.

 

Visiting InvestigatorINSERM U-390, Montpellier, FR, while on a sabbatical leave from I. P. Pavlov First State Medical University (ISPbGMU) and Institute of Physiology of RAS (INFRAN). Co-PI, INSERM-funded Collaborative Biomedical Research with Central and Eastern European Countries. Ended up the popular yet wrong theory on activation of ATP-inhibited weak inward rectifiers by GTP-binding proteins (G proteins). Uncovered the Mg·GTP-affected but G-protein-independent stimulation of isolated KATP, suggesting their intrinsic, CFTR-like, hydrolytic activity before any biochemical data suggesting the ATPase activity of any ABCC-coded protein. 1996.

 

Senior Scientist and Leader of Molecular Cardiology Group at the I. P. Pavlov State Medical University and Institute for Physiology RAS in Saint Petersburg (ISPbGMU and INFRAN). Fellow of the French Ministry of Higher Education and Research at INSERM Physiopathologie Cardiovasculaire. PI, Russian Foundation for Basic Research (RFBR) Program Molecular Mechanisms of Cardiac KIRs Regulation Under Pathophysiological Conditions. Led the International Collaborative Project Purinergic Modulation of Cardiac ATP-sensitive K+ Channels Channels, supported by the Foundation for Medical Research, FMR, in France. Investigated effects of extracellular ATP and its analogs on sarcolemmal P2X and background Kcurrents. Revealed a new signaling pathway from P2Y-purinoceptors to sarco-KATP. Discovered hybrid KATP in developing neonatal cardiomyocytes. 1994-6.

 

Scientist, Interdepartmental Laboratory for Cellular Physiology and Biophysics (ILCPB) a.k.a. Laboratory of Biophysics of Living Cell at VMA, Medical Department of MoD, and RAM/S. PI, Russian Foundation for Fundamental Investigations (later RFBR) Program Molecular Physiology of Metabolism-dependent Cardiac K+ Inwardly Rectifying Channels. Co-PI, Collaborative project with Institute of Cytology RAS Ion Channels in Osmotic Regulation, focused on voltage-gated K+ delayed rectifiers in human lymphocytes and stretch-activated Cl- channels in dividing K562 and Jurkat cells during regulatory volume decrease (RVD) related to onco-invasiveness and cancer aggressiveness. 1993-4.

 

Junior Scientist, a.k.a. "Junior Scientific Researcher", ILCPB. Combined advanced electrophysiological, biophysical and in situ live-cell microscopy methods to determine effects of microwaves, ultrasound and other, including DoD-relevant, physical and chemical factors on pacemaker cells. Investigated modulation of native cardiac strong inward rectifiers as well as ATP-inhibited and Na+-activated weakly inwardly rectifying potassium channels by non-ionizing radiation, heat and cold, non-permeate cations, changes in ionic strength, intra- vs. extracellular acidosis and alkalosis, and other common stimuli, at the single-channel kinetics level. Recorded K+ efflux dynamics in cardiocytes upon hypoxia. Identified KATP in human ventricular cells (in collaboration with then Professor and Chief of Kupriyanov Cardiovascular Surgery Clinic, later President of VMA, General-Colonel of Military-Medical Service, Laureate of the 96' Special International DeBakey Award, Director of Maksimov Stem Cell and Regeneration Center and Sechenov National Center for Thoracic and Cardiovascular Surgery in Moscow, Member of RAMS and eventually of its Presidium, Minister of Health and Medical Industry of the Russian Federation, et cetera, et cetera - an exemplary careerist of Criminal Eltsin's Times, whom then Lieutenant-Commander of Medical Service Babenko refused to continue working with after that Lieutenant-General of Medical Service and Doctor of Theology has tried to defame General-Major of Medical Service, the VMA's VP for Science and Education, V. O. Samoilov, and ~50 Professors and Department Heads of the Academy in order to gain an uncontrolled power and attempt 'commercialization', 'privatization', and, ultimately, sale of its Clinics, Laboratories and other assets. Dr. Babenko has built, in 1988, the USSR's first laboratory bringing together patch-clamp and fast ultra-resolution live-cell digital video-microscopy using advanced components developed at LOMO. The Junior Scientist has related KATP currents and Ca2+-dependent alteration in contractile apparatus of cardiomyocytes during anoxia or inhibition of oxydative phosphorylation or glycolysis. He critically reevaluated the popular adenosine hypothesis of sarco-KATP activation during ischaemia and discovered endopeptides increasing the probability of cardioprotective sarco-KATP opening (in cooperation with M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry RAS and VMA-based V. Kh. Khavinson-directed Cytomed, later Neopharm, subsequently reorganized into the RAMS NW Branch-Integrated Institute of Bioregulation and Gerontology). 1988-92.


RESEARCH GRANT SUPPORT HISTORY (IN CHRONO=LOGICAL ORDER)

The Russian Foundation for Fundamental Investigations (later RFBR) Grant Molecular Physiology of Metabolism Dependent Cardiac K+ Inwardly Rectifying Channels1993-1994, Principal Investigator (PI).


RFBR Grant Molecular Mechanisms of Cardiac KIRs Regulation under Pathophysiological Conditions1994-1996, PI.


The French MESR Grant Purinergic Modulation of Cardiac ATP-sensitive K+ Channels, 1995-1996, Investigator.


The French FMR Grant Analysis of Signaling Pathway from Purinoceptors to KATP Channels in Ischemic Ventricular Cardiomyocytes, 1996, Co-Investigator.


INSERM Grant for Collaborative Biomedical Research with Central and Eastern European Countries: Studies on Molecular Basis for Nucleotide Regulation of Sarcolemmal ATP-sensitive K+ channels1996, Co-PI.


JDRF International Grant Nucleotide-Binding Domains of Sulfonylurea Receptor 1 (SUR1) in Regulation of KATP Channels, 1997-1999, Investigator.


NIH R01 Structure of ATP-sensitive Potassium Channels, 1997-2001, Co-Investigator.


GSK Co-sponsored Analysis of structure-activity relationships in human ABCC8/KCNJ11-coded (SUR1/KIR6.2)4 pancreatic beta-cell KATP, 1997-1999, Co-Investigator.


AHA GIA Cytoplasmic domains of KIR6.2, SUR2A, and their interaction in gating and ATP-inhibition of human cardiac KATP channels1999-2001, PI.


AHA SDG Molecular determinants and mechanisms of potassium channel openers action on human SUR2A/B-containing KATP channels2001-2004, PI.


NIH R01 Studies of Sulfonylurea Receptors and ATP-sensitive Potassium Channels, 2002-2007, Co-PI.


NIH R01 Studies of Sulfonylurea Receptors and KATP Channels, 2005-2009, Co-PI.


NIH R01 ABCC8/KCNJ11 Mechanisms and Diabetes, 2009-2012, PI.


DoD Grant 10305 - Pilot Study 5, 2011-2012, PI.


Pacific Northwest Research Foundation (PNRF) Grant for eXploratory Study 79, 2009-2013, PI.


Privately and anonymously-funded Preliminary Studies for a Novel 'High-Risk, High-Reward' Research Grant, conducted by the PI since 2013.


TEACHING AND MENTORING EXPERIENCES (ALSO IN CHRONO=LOGICAL ORDER PREFERRED BY CLASSICAL EDUCATORS)

Developed an Electrophysiology and Membrane Biophysics Course at the VMA Department of Biological and Medical Physics, 1992.

 

Lectured twenty four MD students at the VMA Department of Biological and Medical Physics, 1993.

 

Co-advised two M.Sc. students from Departments of Biology and Physiology of Saint Petersburg State University during their Thesis Project research in the Interdepartmental Laboratory for Cell Physiology and Biophysics, 1993-4.

 

Created a multimedia Introduction to Ion Channels in Disease for MD/PhD Trainees at Saint Petersburg State Medical University, 1995.

 

Co-mentored one Ph.D. student from the Department of Molecular Physiology and Biophysics and one postdoctoral fellow from the Department of Molecular and Cellular Biology, BCM, 2000-6.


Trained one Postdoctoral Researcher in single-channel current analysis, in 2009, and mentored one PhD Research Scientist, in 2010-2, at Pacific NW Research Institute.


Taught no one doing home work by googling yandex and does not want to add such an experience to his CV


HONORS AND AWARDS

  • National AHA Career Development Award, 2001-2005
  • Inclusion in the International Directory "2000 Outstanding Scientists of the 20th Century" by International Biographical Center, Cambridge, UK, and in Directories of American Biographical Institute and "Who's Who" in Science, 2000 

  • Fellowship from Juvenile Diabetes Research Foundation International, 1997-1999
  • Travel Award from UNESCO and International Union for Applied Biophysics, 1996
  • INSERM Award Action Specifique avec les Pays d'Europe Centrale et Orientale dans Domaine de la Recherche Biomedicale, 1996
  • Award from Fondation pour la Recherche Medicale, 1996
  • Fellowship from Ministere de l'Enseignement Supérieur et de la Recherche, 1995
  • Outstanding Young Investigator Travelship from European Science Foundation, 1994
  • International Science Foundation Travel Awards, 1993 and 1994
  • Soros' Award for Excellence of a Young Scientist in Fundamental Research, 1993
  • Gold Medal from VMedA of Ministry of Defence, 1988
  • VMA Silver Key for Medical Student Research Project, 1988
  • Academic I. P. Pavlov MD Scholarship, 1986-1988
  • Valedictorian Gold Medal from the USSR Ministry of Education allowing early testing for admission to VMA, 1982
  • Golden Key in a regional Chemistry Olympiad, Chekhov, Moscow region, 1982
  • The "Golden Student" didn't get even a Bronze Pin at the All-Union Chemistry Olympiad, held in one of his mind-blowing auditoriums at Lomonosov Moscow State University, in 1982.


SCIENTIFIC REVIEWING

AD HOC SCIENTIFIC RESEARCH FUNDING AGENCIES:

  • National Institutes of Health
  • National Science Foundation
  • American Diabetes Association
  • American Heart Association
  • The Wellcome Trust
  • British Heart Association
  • Scottish Hospital Endowments Research Trust
  • Russian Foundation for Fundamental Investigations 

AD HOC SCIENTIFIC JOURNALS:

  • Journal of Clinical Investigations
  • Proceedings of the National Academy of Sciences 
  • Diabetes
  • Circulation 
  • Circulation Research
  • FASEB Journal
  • Journal of Clinical Endocrinology and Metabolism 
  • Molecular Pharmacology
  • Human Molecular Genetics
  • Journal of Physiology (London) 
  • Biophysical Journal 
  • Journal of General Physiology 
  • FEBS Letters 
  • Journal of Molecular and Cellular Cardiology 
  • Diabetologia
  • Pediatric Diabetes
  • British Journal of Pharmacology
  • Nature Review Endocrinology
  • Expert Opinion on Investigational Drugs
  • Trends in Molecular Medicine (Cell Press)
  • The Scientist prefers to scrutinize selected manuscripts for multiple top disciplinary scientific journals, rather than to review rapidly multiple papers for a few "broad auditorium" magazines, e.g. Nature, long-term Impact Factor of which is lower than that for more specialized scientific journals, e.g. Cell and The New England Journal of Medicine. While admiring Science (mostly for publishing Original Research Articles on cloning of SUR1 and of real, not fake "rat KATP" from OHSU, accepted by Nature, which also published "promiscuous SUR1", and other "exciting" British scientific fiction stories, the Scientist does not measure other Scientists' impact by the number of their papers accepted by Science's Editors who often pick everyone's eyes-catching, max ad$-generating  "fashionable science".
           

OTHER ACADEMIC RESPONSIBILITIES, PROFESSIONAL SERVICE, AND LEADERSHIP EXPERIENCE

  • Chairman, Student Research Association, VMA Department of Biological and Medical Physics, 1988
  • Lieutenant (1988-90) and Lieutenant-Commander (1991-4) of Military Medical Service, The NW Region
  • Scientific Secretary, Problem Commission on General and Cell Physiology of RAS, 1993-4
  • Chair, "Ion Channel Regulation" Symposium, Biophysical Society, 2003
  • Chair, "Potassium Inward Rectifiers" Symposium, Biophysical Society, 2004
  • Member of Faculty Search Committee, Pacific Northwest Research Institute (PNRI), 2009
  • Recruiter of Research Staff for PNRI, 2009-10
  • Presenting PI at Pacific Northwest Research Foundation's Board of Trustees Meetings, 2009-10
  • Faculty Participant of Fundraising Events for PNRF, 2009-13
  • A co-initiator of the post-Great Recession Fundraising Campaign to support Private Nonprofit Research Investigations at PNDRI, 2009
  • A pro bono consultant for an anonymous Global Search of Probands with Rare Syndromes, 2013-

MEMBERSHIP OF PROFESSIONAL SCIENTIFIC SOCIETIES, FOUNDATIONS AND ASSOCIATIONS 

  • Biophysical Society, 1995 -
  • Juvenile Diabetes Research Foundation International, 1999-
  • American Association for Advancement f Science, 1999-
  • American Diabetes Association, 2000
  • American Heart Association, Basic Cardiovascular Science Council, 2001-
  • American Society for Biochemistry and Molecular Biology, 2002 -
  • American Physiological Society, 2002
  • Dumped Research Organizations, Foundations and others Institutions spending increasingly on their executives while decreasingly on Academic Research.


INTERNATIONAL SCIENTIFIC MEETINGS (*ATTENDED TO GIVE A LECTURE OR CONTRIBUTE TO A WORKSHOP ETC)

            2013    Annual Meeting of the Biophysical Society, Philadelphia, PA

            2012    Annual Meeting of the Biophysical Society, San Diego, CA

            2011    Annual Meeting of the Biophysical Society, Baltimore, MD

            2010    The 16th World Congress of Basic and Clinical Pharmacology - WorldPharma2010, Focused                                Conference “Ion channelopathies: new windows on complex disease and therapy”,                                              Copenhagen, Denmark* 

            2010    Keystone Symposium on Diabetes, Whistler, British Columbia, Canada*           

            2010    The 3rd FEBS Special Meeting on ABC Proteins: From Multidrug Resistance to Genetic                                        Diseases, Innsbruck, Austria*

            2010    The Annual Meeting of The Biophysical Society, San Francisco, CA

            2009    The Annual Meeting of The Biophysical Society, Boston, MA.

            2007    The Annual Meeting of The Biophysical Society, Baltimore, MD.

2006    The Gordon Research Conference on Ligand Recognition & Molecular Gating, Il Ciocco, Italy

2006    The Annual Meeting of The Biophysical Society, Salt Lake City, UT.

2005    The Annual Meeting of The Biophysical Society, Baltimore, MD.

2004    The Gordon Research Conference on Ligand Recognition & Molecular Gating, Ventura, CA.

2004    The Annual Meeting of The Biophysical Society, Baltimore, MD*.

2003    The Annual Meeting of The Biophysical Society, San Francisco, CA*.

2002    The Gordon Research Conference on Ion Channels, Tilton School, NH.

2002    The Gordon Research Conference on Ligand Recognition and Molecular Gating, Il Ciocco,                    Italy.

2002    The Annual Meeting of The Biophysical Society, Boston, MA*.

2001    The XXXIXth World Congress of Physiological Societies "From Molecule to Maladie" -                              Workshop on KATP Channels, Christchurch, New Zealand*.

2001    The XXXIXth World Congress of Physiological Societies "From Molecule to Maladie" -                              Satellite Symposium "Structure and Function of Ion Channels", Leura, Australia.

2001    The Annual Meeting of The Biophysical Society, Boston, MA.

2000    The Gordon Research Conference on Ion Channels, Tilton School, NH.

2000    The Keystone Meeting on Potassium Channels, Granlibakken, CA.

2000    The Annual Meeting of The Biophysical Society, New Orleans, Lousianna.

1999    The "Ion Channel Structure and Function" Conference in Yale University, New Haven, CT.

1999    The Annual Meeting of The Biophysical Society, Baltimore, MD.

1998    The 2nd International Conference on ATP-sensitive Potassium Channels and Diseases,                            St. Charles, IL*.

1998    The Gordon Research Conference on Cardiac Regulatory Mechanisms, Colby, NH.

1998    The Gordon Research Conference on Ion Channels, Tilton School, NH.

1998    The XIIIth World Congress of Cardiology, Rio de Janeiro, Brazil.

1998    The Annual Meeting of The Biophysical Society, Kansas City, Missouri.

1997    The Annual Meeting of The Biophjysical Society, New Orleans, Lousiana.

1996    The 20th Meeting of the European Working Group on Cardiac Cellular Electrophysiology,                        Essen, Germany*.

1996    The XIIth International Biophysics Congress, Amsterdam, The Netherlands*.

1995    The 19th Meeting of the European Working Group on Cardiac Cellular Electrophysiology                       "Potassium Channels in Normal and Pathological Conditions", Leuven, Belgium*.

1995    The All-Russian Conference "Ionic Homeostasis and Cellular Functions", St. Petersburg,                        Russian Federation*.

1995    The Annual FASEB Meeting, Atlanta, GA.

1994    The ESF Conference on Cardiac Electrophysiology "From the ionic channel to arrhythmia                    mechanisms: Role of potassium channels", Crete*.

1994    The 1st International Symposium organized by the Problem Commission on General and Cell                Physiology, Russian Academy of Sciences, Leningrad reg., Russian Federation*.

1993    The 1st International Conference on ATP-sensitive K+ Channels and Sulfonylurea Receptors,                Houston, TX.

1993    The All-Russian Conference on Cardiology, St. Petersburg, Russian Federation*.

1992    The 2nd USSR-USA conference on Ion Channels, a.k.a. "The second Kostyuk - Hille Meeting",               Bogomoletz Institute of Physiology, Kiev, then USSR.

1992    The All-Union Conference "Regulation of Physiological Functions", then Leningrad, USSR*.



REPRESENTATIVE PUBLICATIONS

MANUSCRIPTS IN PEER-REVIEWED JOURNALS (*THE CORRESPONDING AUTHOR ON ORIGINAL RESEARCH ARTICLES):


Babenko A. P.* Gating and pharmacology of all possible human KIR6.2V59X-based channels, including KATP from permanently diabetic subjects with epilepsy and developmental problems. Under re-submission.


Babenko A. P.* and Vaxillaire M. Mechanism of KATP hyperactivity and sulfonylurea tolerance due to a diabetogenic mutation in L0 helix of sulfonylurea receptor 1 (ABCC8). FEBS Letters. 2011. 585: 3555-3559.


Babenko A. P.* A novel ABCC8(SUR1)-dependent mechanism of metabolism-excitation uncoupling. J Biol Chem (Accelerated Publication). 2008. 283: 8788-8782.

 

Babenko A. P*.,  Polak M*.,  Cavé H.,  Busiah K.,  Czernichow P.,  Scharfmann R.,  Bryan J.,  Aguilar-Bryan L., Vaxillaire M., Froguel P. Activating mutations in the ABCC8 gene in neonatal diabetes mellitus. N Engl J Med. [see Editorial] 2006. 355: 456-466.

 

Babenko A. P. KATP channels “vingt ans apres”: ATG to PDB to Mechanism. Journal of Mol Cell Cardiol (Focused Issue KATP Channels: From Molecules to disease) 2005. 39: 79-98.


Bryan J., Crane A., Vila-Carriles W., Babenko A. P., Aguilar-Bryan, L.  Insulin secretagogues, sulfonylurea receptors and KATP channels. Curr Pharma Design. 2005. 11: 2699-716.

 

Bryan J, Vila-Carriles W. H., Zhao G., Babenko, A. P., Aguilar-Bryan, L. Toward linking structure with function in ATP-sensitive K+ channels. Diabetes 2004. 53: S104-S112.

 

Babenko A. P.* and Bryan J. SUR domains that associate with and gate KATP pores define a novel gatekeeper. J Biol Chem (cover featured Accelerated Publication). 2003. 278: 41577-41580.

 

Babenko A. P.* and Bryan J. SUR-dependent modulation of KATP channels by an N-terminal KIR6.2 peptide  Defining intersubunit gating interactions. J Biol Chem. 2002. 277: 43997-44004.

 

Babenko A. P.* and Bryan J. A conserved inhibitory and differential stimulatory action of nucleotides on KIR6.0/SUR complexes is essential for metabolism-excitation coupling by KATP channels. J Biol Chem. 2001. 276: 49083-49092.

 

Babenko A. P.*, Gonzalez G., Bryan J. Hetero-concatemeric KIR6.X4/SUR14 channels display distinct conductivities, but uniform ATP-inhibition. J Biol Chem (Accelerated Publication). 2000. 275: 31563-31566.

 

Babenko A. P.*, Gonzalez G., Bryan J. Pharmaco-topology of sulfonylurea receptors: Separable domains of the regulatory subunits of KATP channel isoforms are required for selective interaction with K+ channel openers. J Biol Chem (Accelerated Publication). 2000. 275: 717-720.

 

Babenko A. P.*, Gonzalez G., Bryan J. The tolbutamide site of SUR1 and a mechanism for its functional coupling to KATP channel closure. FEBS Letters (cover featured). 1999. 459: 367-376.

 

Sharma, N., Crane A., Clement IV J. P., Gonzalez G., Babenko A. P., Bryan J, Aguilar-Bryan L*. The C-terminus of SUR1 is required for trafficking of KATP channels. J Biol Chem. 1999. 274: 20628-20632.

 

Babenko A. P.*, Gonzalez G., Bryan J. Two regions of SUR specify the spontaneous bursting and ATP-inhibition of KATP channel isoforms. J Biol Chem. 1999. 274: 11587-11592.

 

Babenko A. P.*, Gonzalez G., Aguilar-Bryan L., Bryan J. Sulfonylurea receptors set the maximal open probability, ATP-sensitivity and plasma membrane density of KATP channels. FEBS Letters. 1999. 445: 131-136.

 

Babenko A. P.*, Gonzalez G., Bryan J. The N-terminus of KIR6.2 limits spontaneous bursting and modulates the ATP-inhibition of KATP channels. Biochem Biophys Research Communications. 1999. 255: 231-238.

 

Babenko A. P., Aguilar-Bryan L., Bryan J. A view of SUR/KIR6.X, KATP channels. Annu Rev Physiol. 1998. 60: 667-687.

 

Babenko A. P.*, Gonzalez G., Aguilar-Bryan L., Bryan J. Reconstituted human cardiac KATP channels: Functional identity with the native channels from the sarcolemma of human ventricular cells. Circ Res. 1998. 83: 1132-1143.

 

Aguilar-Bryan L., Clement IV J. P., Gonzalez G., Kunjilwar K., Babenko A. P., Bryan J. Toward understanding the assembly and structure of KATP channels. Physiological Reviews. 1998. 78: 227-245.

 

Babenko A., Vassort G*. Enhancement of the ATP-sensitive K+ current by extracellular ATP in rat ventricular myocytes: Involvement of adenylyl cyclase-induced subsarcolemmal ATP depletion. Circ Res. 1997. 80: 589-600.

 

Babenko A. P., Vassort G.* Purinergic facilitation of ATP-sensitive potassium current in rat ventricular myocytes. British J Pharmacol. 1997. 120: 631-638.

 

Babenko A. P.*, Kazantseva S. T., Samoilov V. O. Adenosine does not play a fundamental role in activation of KATP currents in rat ventricular cardiomyocytes. Biologicheskie Membrany. 1996. 13(1): 19-28.

 

Babenko A. P.*, Vereninov A. A., Glushankova L. N., Romanova Yu. V. Time course of plasma membrane chloride conductance of Jurkat cells during their osmotic swelling. Cytology. 1995. 37(4): 84.

 

Babenko A. P.*, Romanove YU. V. Activity of the single voltage-gated potassium channels in human B lymphocytes analyzed under the conditions of intact intracellular milieu. Uspekhi Fiziologicheskikh Nauk. 1994. 25(1): 46.

 

Babenko A. P.*, Samoilov V. O. Functioning the K+ channels opening in ventricular cardiomyocytes sarcolemma upon hypoxia. Biologicheskie membrany. 1994. 11 (1): 35-44.

 

Babenko A. P.*, Samoilov V. O., Kazantseva S. T. Potassium channels in the cardiomyocyte sarcolemma: Initial opening under the influence of hypoxia. Basic and Applied Myology. 1992. 2: 317-324.

 

Babenko A. P.*, Kazantseva S. T., Khavinson V. Kh. Activation of ATP-sensitive K+ channels of cardiomyocytes by endogenous cardiopeptides. Bulleteni Exper Biol Med. 1992. 114: 980-984.

 

Babenko A. P.* and Cherniakov G. M. The characteristics of the reactions of excitable tissue to combined exposure to microwaves and low-intensity ultrasound. Gig Tr Prof Zabol. 1992. 5: 19-21.

 

Babenko A. P.*, Samoilov V. O., Kazantseva S. T., Shevchenko Yu. L. ATP-sensitive K+-channels in the human adult ventricular cardiomyocytes membrane. FEBS Letters. 1992. 313: 148-150.

 

Babenko A. P.* and Samoilov V. O. The reaction to hypoxia of ATP-sensitive K+ channels in rat cardiomyocytes. Fiziol Zh SSSR Im I. M. Sechenova. 1991. 77 (11): 55-59.


Babenko A. P. acknowledges that the first homologous KATP was defined in Naunyn-Schmiedeberg's Archives of Pharmacology, not in Nature, and the Nobel-winning "patch-clamp" method was originally described in another "specialized" German journal, Pflügers Archiv.


Babenko A. P. reminds that the retracted Cloning and functional reconstitution of a rat KATP, as well as the similarly artificial and tenure-facilitating Promiscuity of SUR toward inward rectifiers, were delivered in the strikingly similar British.

Book chapters:

Babenko A. P., Sharma N., Aguilar-Bryan L., Gonzalez G., Bryan J. Coupling between SUR1 and KIR6.2 specifies properties of b-cell KATP channels. pp. 44-60 in Molecular Pathogenesis of MODYs, edited by F. M. Matschinsky and M. A. Magnuson. Frontiers in Diabetes. Vol. 15, Karger, Basel, 2000.

 

Babenko A. P. Testing the adenosine-activatability of the ATP-sensitive potassium (KATP) current in neonatal and adult rat ventricular cardiomyocytes. pp. 322-325. In: Potassium channels in normal and pathological conditions, Eds: Vereecke J., van Bogaert P.P. and Verdonck F. Leuven, University Press, Leuven, 1995.

 

Samoilov V. O., Babenko A. P., Kazantseva S. T. Heterogeneity of mechanisms of cardiac potassium channels activation under pathophysiological conditions. pp. 146-156. In: Actual Problems of General Toxicology (In Russian). St. Petersburg. 1995.

 

Babenko A. P., Romanova Yu. V., Babenko I. M., Vereninov A. A. Reaction of ionic permeability of K562 cell plasmalemma on hypotonicity. pp. 21-32. In: Actual Problems of General and Marine Toxicology. MMA, St. Petersburg, 1995.

 

Babenko A. P., Kazantseva S. T., Romanova Yu. V., Samoilov V. O. Molecular mechanisms of ATP-sensitive potassium channels activation in cardiomyocytes sarcolemma during hypoxia. pp. 24-35. In: Ecological and Physiological Problems of Adaptation (In Russian). Moscow, 1994.

 

Cherniakov G. M., Korotchkin V. L., Babenko A. P., Bigdai E. V. Responses of biosystems with different level of integrity to low-intensive UHF ratiation. pp. 140-167 in: Millimeter Waves in Medicine and Biology (In Russian). Moscow, 1989.

Selected abstracts in refereed journals (*THE CORRESPONDING AUTHOR):

Babenko A. P.* and Vaxillaire M. The predominant mechanisms of pathogenic hyperactivity of mutant ABCC8/KCNJ11-coded KATP channels. Biophys J. 2011. 96(1) Pt. 2: on-line.

Babenko A. P.* Diabetogenic ABCC8/KCNJ11: Mechanisms to personalized treatment. Basic and Clinical Pharmacology and Toxicology. In press.

Babenko A. P.* How do mutations in M0 of KCNJ11 produce diabetes? Biophys J. 2010. 95(1) Pt. 2: on-line.

Babenko A. P.* How do mutations in the L0-linker of ABCC8 produce neonatal diabetes? Biophys J. 2009. 94(1) Pt. 2: on-line.                                                                        

Babenko A. P.* and Zhao G. Mechanisms of IKATP hyperactivation by diabetogenic mutations in SUR1. Biophys J. 2007. 92(1) Pt. 2: on-line.                                                                        

 

Babenko A. P.* and Zhao G. KIR6.2X59 clarify the gating mechanism in intact and DEND KATP channels. Biophys J. 2006. 90(1) Pt. 2: on-line.

 

Babenko A. P.* The open time of KATP pore logarithms its gatekeepers-dependent burst time via “one way” coupling mechanism. Biophys J. 2005. 88(1) Pt. 2: 177a.

 

Babenko A. P.* and Bryan, J. Mini-KATP reveal a novel gatekeeper for long K+ pores. Biophys J. 2004. 86(1) Pt. 2: 177a.

 

Babenko A. P.* and Bryan, J. Studies on cloned human KCNJ8: Lessons about KNDP vs classic, hybrid, and “mitochondrial KATP“ channels. Circulation. 2003. On-line.

 

Babenko A. P.* and Bryan, J. TMD0-L0 links the SUR ATP-binding core to the KATP pore. FASEB J. 2003. 17: 369.11.

 

Babenko A. P.* and Bryan, J. Kir6.0/SUR interactions stabilizing closed KATP channels. Biophys J. 2003. 84(2) Pt. 2: 81A.

 

Babenko A. P.*, Crane A., Vila-Carriles, W., Aguilar-Bryan, L., Bryan, J. Interactions of the 2nd generation sulfonylureas with KATP channels. The Pharmacologist. 2002. 44: A189.

 

Babenko A. P. * and Bryan J. Can heteromultimerization of KIR6.0 subunits up-regulate KATP channel activity in vivo? Biophys J. 2002. 82(1) Pt. 2: 181A.

 

Babenko A. P.* Perturbations of KIR6.0/SUR questioning the interburst closed state-delimited binding of ATP to KATP channels. Biophys J. 2001. 80(1) Pt. 2: 625A.

 

Babenko A. P.* and Bryan J. The ATP-inhibitory gating machinery is conserved in KATP, KNDP, and all possible hybrid KIR6.0/SUR4 channels. Biophys J. 2001. 80(1) Pt. 2: 512A.

 

Babenko A. P.* and Bryan J. Functional topology of the regulatory subunits of KATP channels. Biophys J. 2000. 78(1) Pt. 2: 463A.

 

Babenko A. P.*, Gonzalez, G., Bryan J. The mechanism of high-affinity sulfonylurea-inhibition of (SUR1/KIR6.2)4 channels: Uncovering functional coupling between the regulatory and pore forming subunits in KATP channel gating. The Physiologist. 1999. 42(4): A2.

 

Babenko A. P.*, Bryan J. KIR6.2 and sulfonylurea receptors share determinants of ATP inhibitory gating of KATP channels. Biophys J. 1999. 76(2): A14.

 

Babenko A. P.*, Gonzalez, G., Aguilar-Bryan, L., Bryan J. Reconstituted human cardiac ATP-sensitive K+ channel: Functional identity with the native channels in human ventricular cells. Journal of The American College of Cardiology. 1998. 31(5); Supplement C: 108C.

 

Babenko A. P.* and Bryan J. What have we learned from C-terminus truncated KIR6.2 channels? Biophys J. 1998. 74(2): A114.

 

Babenko A. P.* and Vassort G. Agonist-independent, GTP-induced stimulation of cardiac KATP channels. Biophys J. 1997. 72(2): A249.

 

Babenko A. P.* and Vassort G. P2-purinoceptors-mediated enhancement of cardiac ATP-sensitive K+ channel (KATP) current. Progress in Biophysics and Molecular Biology. 1996. 65(1): 89.

 

Babenko A. P.* and Vassort G. Can cytoskeleton actin stabilization and tyrosine kinase inhibition affect cardiac KATP channels run-down and reactivation by MgATP in inside-out membrane fragments?  Biophys J. 1996. 70(2): A398.

 

Babenko A. P.*, Romanova Yu. V., Vereninov A. A., Glushankova L. N.  Time course of plasma membrane chloride conductance  (gCl-) in Jurkat cells during osmotic swelling at cytoplasm preservation. FASEB Journal. 1995. 9(3): A389.

 

Samoilov V. O., Babenko A. P.*, Kazantseva S. T. Modulation of cardiac glibenclamide-sensitive K+ currents during metabolic inhibition: Perforated patch-clamp study. FASEB Journal. 1995. 9(3): A388.

 

Babenko A. P.*, Kazantseva S. T., Samoilov V. O. Adenosine-triphosphate-sensitive potassium channels do not play a fundamental role in adenosine-activated potassium currents in rat and human cardiomyocytes. Drug Dev Res. 1994. 31 (4): P32.

 

Babenko A. P.*, Kazantseva S. T., Samoilov V. O. Does adenosine activate ATP-sensitive potassium currents in neonatal and adult ventricular cardiomyocytes? Cell Biology International. 1994. 18 (5): 404.


Babenko A. P. shared as many as possible of his personal discoveries and turned-to-be-true predictions using as few as possible gigabits of the public storage called pubmed. 


Babenko A. P. never submitted to any British Editor paid for weekly masterpieces "going viral" until they are withdrawn from the US-inflated information supermarket before causing death or another complication more noticeable than countless millions of dollars wasted on reproducing so many-exciting artifacts.


Babenko A. P. emphasizes that most of publicly accessible messages deliver no or very little information, scientifically definable as the amount of ambiguity eliminated upon receiving the message.



LANGUAGES (BESIDES THE PROFESSIONAL JARGON-OVERLOADED AMERICAN ENGLISH:)

Russian (родной Mother-language, the richest and most powerful of all, indeed);

Ukrainian (розумію as Father-language, which, sadly, is not used anymore to write or say anything worth reading or hearing);

Latin (limited to what every old Medical and/or Military Academy graduate uses to be laconic);

Deutsche Sprache (fast fergessen, entshuldigen Sie mir bitte, but restorable in the right environment).

Americans-invented Lexicons, including the Wordless one, spread mainly by Gen Y singlefingeral typists (extremely limited), and the popular, virally spread orally, mostly by Millennial Pop-Cuties with the XXXtremely restricted vocabulary (Do not click on the latter link if you are under 18!).


WORK-RELEVANT PERSONAL CHARACTERISTICS AND ABILITIES

Minimally opportunistic maximalist; conservatively contra-neo-liberal, respecting every progressive state industrialism that over-performs every post-/imperial monopolism; agile "harnessing slowly to run fast"; introversively sanguineselectively eclectic; Med food-preferring omnivorous, highly-tolerant to non-filtered anti-aging and cardioprotective Cabernet Sauvignon, preferring the White Muscat of the Red Stone over similarly priced Royal Tokay and Sauterne for dessert; non-smoker; modestly OD near-sighted, slightly OS presbiopic, not needing any other prescription; opposing drug advertisement on TV, arm sells to mad, for-profit jails, and others "only-in-America" legalized idiotic things; aggressively anti-militaristic; religiously atheistic and gnosticPAS-accepting pro-choice proponent, who self-administered and re-received twice the eventually perfected Variola vera vaccine, got immune to almost everything else on the planet following the wisdom "everything what does not kill a man only makes him stronger", and gave many litters of his almost universally receivable blood to save several Rh+ who've learned, hard way, a few things Gruppa Krovi [Blood Type] actually tells us. Dr. Andrey Petrovich Babenko is an unapologetically straight guy who carries a few high-penetrance irresistible eye-color polymorphisms, agrees with the much more powerful man on many things, including that vision, and worships only his Prima Donna with sombre Yeux Revolver,

 

Илона Михайловна Бабенко

Ilona Michailovna Babenko,

 

who was born Smagarinskaya on that special year's Aries-Taurus Cuspyet married, on the 1st of Tevet, 5751the self-introduced Gemini, whom she brought down to his left knee, to bleed on 9 roses, in his med uniform, under Rostral Columns, by falling for him like this, and like this, and like this, and like this, and like this, and like that, not only in and near Piter, Moscow, Sevastopol and Gagra, then USSR, because "everything can be given up for that" true love from the moment "he stepped down, trying not to look long at her, as if she were the sun, yet he saw her, like the sun, even without looking."


EDUCATION

B.S./M.Sc. in Biology/Human and Animal Physiology, including Physiology of Lab-related species, e.g. Her sob, from Saint Petersburg State University. Thesis Study: "Transmembrane redistribution of monovalent cations and changes in ion fluxes through plasma membrane of Jurkat and K562 cells under hypotonia" at the Institute of Cytology RAS (Co-Advisor - Professor of Cell Biology A. A. Vereninov), 1994.

                                                                                                                     

RESEARCH POSITIONS AND EXPERIENCE (ANTI-CHRONO-LOGICALLY)

Research Scientist II, University of Washington in Seattle (UW) Diabetes and Obesity Center of Excellence directed by Professor M. W. Schwartz, MD. Works with several PIs conducting federally and non-federally funded projects on molecular mechanisms of metabolic disorders, including atherosclerosis, one of the commonest diseases, first modeled and investigated by the not discretited Nobel Prize (in Physiology or Medicine)-deserving Medical Scientist, Military Doctor, State Activist, and Academician, Nikolay Nikolaevich Anichkov, Full Professor of her husband's Alma Mater and Honorary Professor of other World's top Academies and Universities. 2008-

Research Scientist 2, UW Department of Medicine, Division of Metabolism, Endocrinology and Nutrition. Mastered in mass spectrometry under supervision of Dr. T. Vaisar, PhD, at the UW Medicine Mass Spectrometry Resource, directed by Professor J. W. Heinecke, MD, and applied proteomics techniques and additional methods to NIH-funded basic and translational research on apoA-I lipoprotein in the pathogenesis of atherosclerosis. 2007--8.

Research Assistant II, Section of Cellular Oncology (Chief - Professor W. N. Hittelman, MD), Department of Experimental Therapeutics, Division of Medicine, The University of Texas M. D. Anderson Cancer Center (UT MDACC), Houston. Studied Cyclin D1 (CD1) polymorphisms in Barrett’s esophagus/adenocarcinoma. Analyzed CD1 gene amplification in biopsy samples. Developed ecdysone-inducible expression system for CD1 in MCK cells. Tested whether cortactin is a predictor of aggressive phenotype in head and neck cancer. Compared gastrin secretion from different esophageal tumor cell lines using ELISA. Analyzed the hedgehog pathway in esophageal tumor cell lines and effects of bile acids on the hedgehog signaling. Examined Gli-1 and nf-kb activity in anal cancer. 2001-7.

Research Assistant I, Section of Cellular Oncology, Department of Experimental Therapeutics, Division of Medicine, UT MDACC. Optimized ecdysone-inducible expression system for CD1 in WI38SV40 cells. Under Dr. J. G. Izzo, PhD, supervision, correlated CD1 polymorphisms and risk of cancer development in the upper aerodigestive tract. 1999–2001.

Research Assistant, at INSERM Unit of Cardiovascular Physiopathology in Montpellier, then directed by Dr. G. Vassort, D.Sc., and in Saint Petersburg State Medical University Molecular Cardiology Group, then led by Dr. A. P. Babenko, MD, PhD. Assisted PIs in conducting International Collaborative Research Projects funded by the National Institute of Health & Medical Research and RFBR. Assisted Dr. M. Puceat, D.Sc., now Director of INSERM Program on Physiopathology of Cardiac Development, in preparing the primary culture of neonatal rat cardiocytes for viral gene transfer, microinjections and electrophysiological studies conducted by Dr. A. P. Babenko, MD, PhD, HerLove. This was a part-time job while caring for their petite fille Tamara. 1995-6.

Research Assistant (part-time to take care of her then-really-little daughter) at the Institute of Cytology RAS National Cell Line Collection directed by the President of European Tissue Culture Society - Russian Branch, Professor of Cell Biology G. P. Pinaev, D.Sc. Cultured various cell types without antibiotic and conducted mycoplasma testing and cytotoxicity studies. Under supervision of Dr. G. G. Poljanskaya, PhD, karyotyped cell lines derived from solid tumors. Using videomicroscopy, spectro-photometry and ion-flux assay, clarified ionic mechanisms of the regulatory volume decrease in lymphoid and myelogenous cell lines, 1994-5.


LABORATORY TECHNIQUES AND SKILLS

Proteomics techniques: mass-spectrometry, including ESI and MALDI TOF/Quadrupole MS; Tandem MS; HPLC.

Cell biology techniques: tissue culture, including primary culture of freshly isolated mammalian cardiocytes and human lymphocytes; establishing stable cell lines; determining the growth curve; micromanipulation; Nomarski and fluorescence confocal microscopy; tumor cell invasion (Boyden chamber) and wound healing assays.

Molecular biology and biochemistry techniques: DNA and RNA extraction and electrophoresis; DNA sequencing; single strand conformational polymorphism analysis; PCR, RT-PCR, and Quantitative Real Time PCR; molecular cloning; restriction enzyme digestion and agarose gel analysis; preparation of expression vectors; mini and maxi preparation of cDNA plasmids; Northern and Southern blot; in situ hybridization; siRNA; transfection; immunoprecipitation; protein expression and purification; SDS-PAGE, Western blot.

Immunological methods: immunocytochemistry, immunofluorescence staining, ELISA.

 

Radioisotope techniques utilizing 32P labeling, scintillation/gamma counting.

Working with human subjects, including blood samples processing and microdissection of biopsy specimens.

Basic veterinary skills, including simple surgery on rodents.

General laboratory skills, including buffer preparation, sterilization, centrifugation, photo-documenting, record keeping, organizing databases, record keeping, etc.

  

SOFT SKILLS

Microsoft Office, ISI ResearchSoft EndNote, Scanning & OCR Software, Jask Paint Shop Pro Soft, Adobe Acrobat, Illustrator, and other Creative Suit Software Tools.

Advanced image analysis software, including MetaMorph Image Analysis (just basic procedures).

Statistical analysis tools, including Splus 45, SPSS, and Microcal Origin Software (basic procedures only).

 

 

EXPERIENCE IN LAB MANAGEMENT

Maintained records of cell lines and molecular reagents since 1994.

Monitored work flow of laboratory supplies and proper functioning of laboratory equipment since 1994. 

Placed and followed up repair and purchase orders since 2001.

Performed monthly wipe tests and prepared quarterly radiation safety reports for over four years after taking

 a course in Safe Handling of Radioactive Materials in Research and Clinical Laboratories in 2002.

Troubleshooted and optimized PCR, Western blot, immunostaining, and several cell biology assays since 2002.

Supervised three Research Assistants and trained nine PhD students in tissue culture and Western blotting since 2003.

Assisted PIs in collection and preparation of data for grant applications, manuscripts, and scientific presentations since 2003.

Oversaw the radiation safety in the UT MDACC Section of Cellular Oncology in 2006.


Completed a course in Shipment of Biohazard Materials in 2006.

Coordinated research efforts of technicians from collaborating labs in the U.S.A. and abroad since 2008.


 

OTHER JOB EXPERIENCE

Assistant Accountant at then Psychiatric Clinic of the USSR Ministry of Health (part time) while attending then Leningrad State University's Faculty of Biology after not being accepted to then Leningrad First State Medical University [due to an insufficiently-high score in Math Test administered by that formerly Women's Medical University's State Examination Commission]. 1987-8.


LANGUAGES (BESIDES AMERICAN ENGLISH SPOKEN IN MEDICAL RESEARCH CENTERS)

Русский (нативный);

Française (vivant);

(עברית (אבוד


PRO HOBBIES

Cosmétologie and Med Cosmetology.

 

ADDITIONAL ABILITIES AND TALENTS

Ambiversive and cross-cultural enough to help different Investigators collaborate and raise research funding in RU, EU, US and beyond. Able to detect residual traces of fine olfactants, e.g. those distinguishing Chanel No.19 wearers from the rest of 51%, analyze all taste receptors stimuli including Her sob's favorite umami, mix up secret souses bringing every other man to his plate, and, after they all release insulin and other hormones, recite by heart something timelessly wise to save every one of them from dangerous dreams.

 

REPRESENTATIVE RESEARCH PUBLICATIONS

Vaisar T., Tang C., Babenko I., Hutchins P., Wimberger J., Suffredini A.F., Heinecke J.W. Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity. 2015. J Lipid Res. 56: 1519-30.

Izzo J. G., Stewar R. J., Wu X., Ensor J., Babenko I. M., Luthra R., Pan J. Y-J., Correa A. M., Swisher S. G., Chao Clifford K. S., Hittelman W. N., and Ajani J. A. Cyclin D1 G/A870 polymorphism with altered protein expression is associated with early age at diagnosis and aggressive clinical biology of esophageal adenocarcinoma. Under resubmission.

Izzo, J. G., Malhotra U., Wu T. T., Ensor J., Babenko I. M., Swisher S. G., Correa A., Gresalier R. S., Hittelman W. N., Ajani J. A. Impact of cyclin D1 A870G polymorphism in Esophageal adenocarcinoma tumorogenesis. 2005. Semin Oncology. 32: Suppl. 9, 11-15.

Pan, J., Ceron T. L., Babenko I. M., Wu T. T., Swicher S., Correa A. M., Ajani J., Hittelman W. N., and Izzo J. G. Cyclin D1 A870G polymorphism is associated with early onset of Barrett’s adenocarcinoma. 2004. Proceedings of the American Association for Cancer Research. 45: 91.

den Hollander P. L. C., Hittelman W. N., Babenko I. M., El-Naggar A. K., Yost R., Lu T., Hong W. K., and Izzo J. G. Cortactin as a molecular predictor of aggressive phenotype in head and neck cancer (HNC). 2003. Proceedings of the American Association for Cancer Research. 44: 879.

Izzo, J. G., Papadimitrakopoulou, V. A., Liu, D. D., den Hollander P. L. C., Babenko I. M., Keck J., El-Naggar A. K., Shin D. M., Lee J. J., Hong W. K., Hittelman W. N. Cyclin D1 genotipe, response to biochemoprevention, and progression rate to upper aerodigestive tract cancer. 2003. Journal of the National Cancer Institute, 95: 198-205.

Izzo, J., Babenko I., den Hollander P., Hong W. K., Hittelman W. N., and Papadimitrakopoulou, V. A. Cyclin D1 Genotypes: Impact on expression and risk of cancer development in the upper aero-digestive tract (UADT). 2001. Proceedings of the American Association for Cancer Research. 42: 342.

Babenko A. P., Romanova Yu. V., Babenko I. M., Vereninov A. A. Reaction of ionic permeability of K562 cell plasmalemma on hypotonicity. pp. 21-32. In: Actual Problems of General and Marine Toxicology, MMA, St. Petersburg, 1995.


FAVORITE QUOTES FROM MORE POPULAR BIBLIOGRAPHIC SOURCES


"Everyone who uses proverbs will quote this one while speaking against you: 'Like mother, like daughter'.'"

Ezekiel 16:44


"He says, he loves my daughter;

I think so too; for never gaz'd the moon

Upon the water, as he'll stand and read,

As 'twere, my daughter's eyes: and, to be plain,

I think, there is not half a kiss to choose,

Who loves another best."

William Shakespeare


"Yes, I do have a beautiful daughter. I also have a gun, a shovel and an alibi.

A mother's love for her child is like nothing else in the world. It knows no law, no pity. It dares all things and crushes down remorselessly all that stands in its path."

- Agatha Christie, who is also liked by the next Biodata-posting, Gen Y Krasavitsa, 


Tamara Andreevna Babenko



 unrelated to any 'Tamara Babenko' on any Social Media Panel.


According to Tamara Andreevna (Младенец), "there isn't much to curriculate or ré-sumé about the Gen Y Babenko, yet; so just a megabit of Biodata from your "hyperthymesic Krasavitsa" will have to suffice". [NB! Her Bio's Notes in gray are For Truth-seeking Eyes Only!]
                                                                                                                                                                           "Устами Младенца глаголет Истина (Puer Semper dicere Verum/The Child always tells the Truth); adding fantasies to my true story won't make it even a bit more fantastic." - The Gen Y Babenko, Tamar A ndreevna

"The more a daughter knows the details of her mother's life... the stronger the daughter" - Her mother-recited    Anita Diamant


Младенец was conceived in EXtasynot a paintable, sculptable, filmable or gifable act; under the sub-micron ElectroMagnetic Waves-disseminating Waning Gibbous, in the absence of the would-be-interfering USSR-made EMW source. That Act of Love was witnessed by two next brightest objects in the hyper-adrenergic man's mind-blowing night sky, the Mars-opposing Mиp and the Magellan-encountering Venus, both above the Cicada song-echoing Hellenic ruins near this aquatory-guarding citadel under Andreevsky flag. The co-created Wonder was provisionally named ТАМАР/A not after this ancient legend but in memory of the loving man's mother who suc- cumbed to an incurable brain neoplasia, at 41, stoically, like Alcestis, after sending her only child far away to "become α Man, conquer a Disease, surrender to Bellissima, and create with her the next Krasavitsa with our grey-blue eyes."

The so-created [сотворенная] Tamara Andreevna, nicknamed 'КOTЯ' The Nocturnal Creature with iris color SNPs originating from a man who loved in a coastal cave under a palm tree, was born right after the Russian Tamara's Day in Ott Institute, with yeux revolver firing from under already 8 mm-long/0.8 mm-thick lashes, and right on time for the Great Victory Celebration.[Note #1] [For Note #1: The filmed celebration is the one held soon after МИША (The future Recipient of The Nobel Peace Bribe, founded on Untaxed Profits from Sales of an Explosive and most recently discredited by Barack Who approved Record Sales of Newer Explosive-delivering Products to Brutal Regimes keeping Wars going - Untaxed Profits growing) "teared down that [Berlin] Wall" without getting from Ronnie Who Played Yankees Taking Care of Others' Lands a treaty that Wild Westerners Who Amended Any Responsible Use of Arms in Their African Slaves-built Thirteen+ Colonies of Exterminated Unslavable Indians won't expand the indeed-becoming-obsolete NATO toward the every-crashed-aggressor-forgiving Union, that lost >20% of its citizens while saving Civilization, including the 'most civilized West' Europeans who've started every World War from their exceptionally nationalistically and supereconomically run Deutschland über Alles, and then counter-balanced the next Western superpower, the post-FDR States that cynically and repeatedly mass-murdered >200,000 innocent Asians in an idiotic attempt to intimidate Victorious after their Union Marshal - not the Georgian Joseph Dzhugashvili or another mad politician - has already accepted total and unconditional capitulation of the "Dritte Reich" and all its Mussolino-Romanian Fascists, crashed by Russian-speaking before English-talking finally agreed to arrive to sandy beaches of Normandy to deal with just a dozen of demoralized=dead Wehrmacht divisions; collect reparations far-exceeding "enormous" contributions of the American English- and English English-speaking to stopping the Nazi's "undefeatable" worriers-'crusaders' (rather mad animals) from being simply thrown from the Cliffs of Normandy into the English Channel by the Greatest Armed Forces thus eliminating the need for building any wall in Europe; reinterpret the WWII Deciding Events, which they never participated in, for their English-only-speaking Boys and Girls; and finally begin redrawing the post-WWII map of not only the oil-rich Middle East, thus surely inflaming the Cold War for the benefit of their Military-Industrial Complex with its Department of War (shamelessly renamed to "Defense"), National surveillance associations, Secret waterboarding services, Centralized assassination agencies, Bigger-that-Berlin-Wall-Border-Barriers-Above-Preserved-Tunnels builders, et al hypocritical producers of $20,000,000,000,000+ debt, hated by 7,000,000,000+ people, and so "justifiably" consuming a lion share of Federal taxes for their Defense allowing them, exceptionally-aggressive Western parasites, to spread globally to feed on billions of Homo sapiens who have evolved to work for living under the Sun and Zarya-based ISS, not the "IS" enabled by the West for the benefit of their Military-Industrio-Financio-Political "elite"... (Although the footnote might sound "too harsh" to some Westerners, the WWW Administrator-Editor didn't shorten the original, much longer sentence till this point, hoping it might help many mildly or even moderately retarded better understand what the post-WWII Western Opportunists were doing to the world Младенец was born to face, and what's coming next.)]

Next, before the Well Born to the Youngest Faculty Scientist of the Greatest Imperial Medical Academy[Note #2][For Note #2: Tamara is also 1) the only grand-child of a well-remembered Senior Officer - Radioelectronics Engineer of the Greatest Aerospace Forces, and of a Ph.D. Engineer of any aggressor-stopping systems; and 2) the Grand-grand-child of the Resting-in-Honor 1st Rank Captain who fought animals calling themselves "superrace" while mass-murdering not only Slavs and Jews during the WWII, and of an equally Heroic and forever-remembered woman-surgeon who saved thousands of lives not only during the war times] grew up enough to handle Truth about the post-WWII World instead of Мурзилка, the pro-Western Oligarchs-backed post-Coup d'État 'Perevorot'[Note #3] [For Note #3: the one which started at the Summer 'Datcha' of then already-Bribed Mister Gorbachev near the place Tamara was created just a few years earlier and turned to be more bloody than the Great October one which has effectively terminated the WWI and liberated hundreds of millions from the Tyranny comparable to the Prussian, British and French decapitated earlier by much more bloody Revolutions "liked" by Western hypocrites who never lived outside the big island discovered not by the West-celebrated murderous criminal-colonizer Columbus and knew really nothing about the World, and might learn at least something from the Note] interrupted the Era of United Sixteen Sovereign Republics, presentable to religiously brain-washed Westerners as "the Evil USSR Empire". That West-celebrated Dissolution of the Union - again less-bloody that Collapses of every other over-grown Empire - only en-couraged the 'God-blessed' to keep spreading their propaganda radio-waves, weapons of mass destruction, mercenaries, special agents, trained-by-them terrorists presentable to totally brainwashed as "freedom fighters", and anything else needed to destabilize, destroy, divide, and economico-monetarily re-enslave South Slaves, Middle Easterners, East Asians, among others, and export more CIA-designed "liberating revolutions" far beyond the South America. At that critical moment in the World History, the Babenko Family with a beautiful little girl in hands, and undoubtedly preferring evolution to revolutions, decided - for better or for worth - to follow the old tradition of the Great Intelligency and moved to then safer Côte d'Azure then offering Academic yet well funded biomedical research institutes, free yet superb child care, education, health services, and other great things that would begin to disappear under the États-Unis-D.C.-via-District-of-Brussels-controlled, <4%-of-Frenchmen-approved, miserable leadershit. There, in then independent France, la Princesse petite spent some time in l'école maternelle to pick up the Language of Diplomats and let her parents continue their research at INSERM in Montpellier, the hometown of the oldest Faculté de Médecine, where A. Loubatières et colaborants have "accidentally" (because of their rare-nowadays ability to carefully observe, unbiasedly document, and critically analyse pysiopathological events) discovered the hypo-glicaemic action of sulfonamides closing her father's favorite 'Kanäle', thus helping improve lives of billions with Common Diabetes mellitus linked with other "Non-communicated disorders" of now not only Western Civilization.

The next Bio-significant event happened while the Western World was partying in full swing around alcoholic Eltsyn [selling his Motherland like a prostitute, or - when in a brutally drunk butcher's mood - slicing Her and selling piece by piece at ~100 rubles per cent], and returning home was out of question for Babenko whose Alma Matres were prepared for dissection and sale (with their Brains going first) and whose colleagues trying to continue Academic Research in Eltsyn's Russia began forgetting how French, or even Russian, cheeses taste. If memory serves, it happened on the long-awaited Friday eve Tamara was finally pre-conditioned to try 1 mg of Napoleon's favorite Époisses hated by KutuzovSon pèpe, then still a Lieutenant-Commander of Russian Medical Troops in Reserve, returned home from his research lab battle-field early, at 23:59, but without the promised "ultimate gastro-educational test" sample, and instead announced: "Sulfonylurea receptors and ATP-inhibited pore-forming subunits of our obviously tetra-hetero-dimeric KATP have apparently been cloned in the Land of the Rising Sun and the Lone Star State after some HHMI-paid Oregonians and Oxfordians "sold" the PCR-cloned homolog of GIRK1 as the dearest-to-my-heart cardiac KATP to the top British magazine for scientists pursuing a rapid promotion before Krapivinsky with Clapham were able to submit the prove that the homolog is just another subunit of heteromeric G-protein-gated potassium channels! [son pèpe also added something in Mother-Russian Младенец can't translate]" The 5 year-old Tomochka didn't understand how or why the news might affect her or any other's well-being, but her 19-year-older Mommy, fearlessly wearing Chanel No. 19 instead of son mari-prescribed Magie Noire, turned off the stereo "opening her mind" with this Mylène Farmer Hit instead of her own Family Psychosociologist-recommended Edith Piaf, and said "Adieu, la vie en rose." For that unforgettable moment, the Husband-in-Command gave His Goddess a Kiss and whispered in her ear, "Qui, Madame, à la guerre comme à la guerre", the only thing in French he knew. And so, by the next tu fais le pont, His Lady loaded leurprêt-à-a-porter in between boxes labeled 'Babenko Lab Instruments', 'КOTЯ's toys', 'Dom Perignon 1988 for Joe [Bryan] plus 8 Oz from the Heart of Paris for Joe's compañera [Lydia Aguilar] and their cosita [Joanna]', dispatched Kotya to her grandparents in the City of Peter the Great "for a short vacation", toured with her "Not yet Coulomb" Alps-Provence in a just-few-month-earlier-purchased, green gas-over-producing Clio Sport [sorry, neither Tesla nor Bugatti Veyron was available] while awaiting their expedited HB Visas, quickly received them from a charming Russian Consul in Marseille, finished all still-maturing bottles of then-affordable local Cabernet Sauvignon on their flat's veranda offering a panorama with several seven-centuries-old cathedrals on the Mont Pelé background, organized a farewell party for the best French Cardiovascular Researchers around the never-affordable Kamchatka crab meat [which came unexcusably frozen], left "Je désolé" with un gros bisou to the most charming Guy and Research Directeur at Aéroport de Montpellier–Méditerranée, and crossed Her Rubicon, Atlantic, with Andrei never to be Bolkonsky.

A few days later, Tomochka and her grandparents in Piter received the first >2 hour-long phone call from Ilona, briefly reporting that the smaller city of Houston has an infinitely larger number of morbidly-obese, solo-riding trucks originally designed for transporting 2 cows or 1 horse + 2 Mastiffs, through the flat, flooded and over-heated terra with the always over-full stinky Canalization canal in place of a river. But, Houston's Galleria has Ice, can import a few little things made from Barguzin sable, and an average TX size portion of beef will feed Sob, Koshechka and already terribly missed Kotenjka for a week. In a week, the latter meat-lover has finished tasting every Salami, as well as Caviar, from Eliseyev Emporium thus nearly bankrupting her most-loved grandparent [actually, the most unconditionally loved person in the universe], Dyudya, jumped on a Lufthansa Airbus to Charles de Gaulle International, declined upon landing at CDG a 'Welcome back' pack of fromage from a French Customs Officer, a handsom Italian, thus shocking the accompanying her German Stewardess, and took a bigger Airbus to Bush Intercontinental.

When Tamara opened her mouth to breath in 100% humidity at 100 ºF during the post-Khanuka Fiesta upon her delayed arrival at IAH, her sweating Dad - transliterated as Andrey and assembling his system for advanced analysis of pico-Amp currents through the most complex recombinant ion-conducting hetero-multimers in the World's largest medical center with countless Mexican restaurants offering "small" portions of pork sufficiendo to knock-down any legal alien - growled that Andrei Dmitrievich Sakharov, once transliterated as "A. Zukerman" rather than "A Sugar-sweet man who has beaten all US Government-bought German and other European nuclear Nobelists", as well as Sergei Pavlovich Korolev, transliterable only as "The King in rocket building", assembled and tested their big things not in Nice places. The so-aggressively-proactively-disallowed-to-complaint-about-Houston's-climate-and-environment "Not a princess anymore" quietly entered an air-conditioned Elementary leaving no child behind [according to a huge banner hanged over a smaller note asking not to bring automatic weapons inside the exemplary school building]. But there Tamara opened her mouth to say something in Americano in less than two weeks, was urgently tested, and immediately transferred to the top Vanguard G/T School, T. H. Rogers. There Tamara did a bit more to get on the Duke University's Gifted/Talented Children List. Upon moving up to THR Middle, she started reporting for the school newspaper Rampage and won the Silver Key in a Scholastic Writing Competition at the city level. But, since the Golden one made in China from a rapidly-deteriorating yellow plastic went to a Chinese girl who crossed Pacific before picking up any Mandarin from her not less Great Motherland, Tamara realized it's time to refocus on something more challenging and satisfying than Creative Writing in American English for American Awards. So she began helping deaf and multiply impaired children enter the THR Special Education. That's when she realized that, indeed, nothing is more important for humanity than human health, and nothing is more noble than trying to find a cure for still incurable.

While in eighth gradethe Green Card-ed girl accepted an invitation to become a Junior Member of the National Honor Society, believing this will help her get to a pre-med honor program-offering college via a top private high school in Houston. But while interviewed in such a school, she realized that her interviewers are interested mostly in how much her family could give to the establishment directly or via its affiliated church. So, the fast-thinking "angel" immediately confessed that her weekly allowance is zero penny and that she has spent her 50 State Quarters on the Special Edition of "The Da Vinci Code", so she can give literally nada to spiritual followers of those who religiously burned Slavic baby boys while trying to conquer her grand-grand-grand-grand-grand-grand-grand-grand-grand-grand-grand-grand-grand-grand-mother-land, tortured and crucified countless natives during subsequent church-blessed expeditions including transoceanic colonial crusades, drowned all waterboarding-resisting "witches", burned alive Giordano Bruno and many other Great Minds while trying to annihilate not only scientific but any free thinking, and literally blessed many other horrible acts in the name of a possibly existing man reportedly sold for 30 pieces of silver to ancient security services thus opening the era of clandestine vaults, best in Vatican, accumulating precious metals including gold from dental crowns extracted at the God-blessed camp sites aka concentration camps. Not surprisingly, t
he neo-conservative Education Masters shepherding Junior$ of highly-moral American Elite, including Enron
's criminal Executive Officers, 
godly Oil Moguls connected to CIA Global Spec OPs, et cetera, et cetera, instantly lost interest in "such a heretic and venomous girl", who happily ended up, together with other analytically thinking, atheistic, free-minded, telling what they think, and otherwise "not like real Americans" kids from all over the world in the
top Magnet High School, 
Bellaire Senior HS, where she was selected for an International Baccalaureate/Advanced Placement Program
and served as The Three Penny Press Reporter.

To take even better care of her multilinguality and proudly inherited free mindset, Tamara began regularly travel through the recovering, post-Eltsyn ex-Soviet space, its EU-wanted Baltic Republics, seeking- and not-seeking-EU parts of Scandinavia with >>50% of Norwegian wealth dependent on its Oil Industry not criticized in the West, "neutral" [i.e. everyone's money-storing during every war], et al, critical thinking-stimulating parts of the European Continent before they have gotten "united" to be run via D.C.-like Corrupt District of Brussels
. In 
Her Birth-place City never conquered by any foreign power, Tamara rediscovered many well-preserved Shedevrs of Architecture and Timeless Art, including Impressionism [please acknowledge that d'Orsay's collection was also great, and that Louvre is much bigger than Hermitage, thanks to Napoleon's victories]. Also in St. Petersburg, she over-came jealousy 
to Ballerinas - after learning how hard they work - and felt in platonic love with the most heroic figure skater of her time
. While traveling through different European countries and later through Turkey and beyond, she further 
learned to appreciate the diversity of cultures, religions and political systems, ignore BBC and CNN - The Most Corrupt National News - as well as similarly "independent" and "free" American Press printing spooky lies about what is happening outside their most-militarized-police-secured Homeland taken from gun-less Natives Americans by God-blessed. The critically-thinking girl with the wide-opening, and becoming more grey then blue, eyes quickly learned to distinguish democratic [deleted "direct" here; and referring to a Greek dictionary wouldn't help "exceptionally democratic" any way] elections from electoral farces with co-starring "Democrats" presented as a Donkey of never specified species or gender [a hermaphrodite? Oh, no...] and "Republicans" presented as an Elephant (neither African nor Indian, more likely a mail, most probably red-blue white) to keep Oligarchy chamaeleonica, the deadliest parasite of all, superbly fed, not to become too fat, and never stressed like it happened recently during the latest series of the Farce "The Battle of a female crook pre-selected by established super-delegates versus the established-hating businessman smart enough not to give crap about Russia and its Intelligent President strongly supported by >85% of directly-voting Russian Citizens"]. By the way, thanks to living for long enough in every "Union", Tamara learned to separate patriotism, uniting a nation against aggressors, from militaristic nationalism, producing the latter. The post-Cold War Child grown in both "superpowerful" yet respectfully co-existing countries, and loving to have the best from both, learned to cherish Mиp, meaning both Peace and World in the language of Tolstoy, as no one else. The so educated and enlightened [просвещённая] "Girl of the World" was truly inspired
upon visiting - during one incredible Summer Vacation - Alma Matres of her parents,
 Karolinska Institutet and Harvard Medical School. These experiences and, of course, her heroic grand-grandmother's example, kept the quietly ambitious teen thinking about pursuing a "probably-the-most-challenging" but truly noble career in medicine or in biomedical research, ideally in a place with a better climate than the one she and her parents experienced in the Lone Star State...

And, soon after the record-breaking flooding of Texas Medical Center and separation of its Baylor from Methodist who found Weill in the not-yet-under-the-water NYC,
her 
parents accepted job offers from "Emerald City" of Washington State instead of agreeing to continue sweating in the State of George II Supremely Appointed to Continue His Mission of Killing for Oil and Doing Other Outrageous Things in Cooperation with then
British PetroleumPremier Minister. In the State of the
First and only nonpartisan President of the United States,
Tamara got into
 
located approximately in the middle of the Google Earth-drawn line between the Primary Estates of Gates and Allen Families, and 
was finally naturalized under her father's
name 
not changed even "a bit to something more Anglo-American e.g. Babenkoff" in 
the process 
[Would Pushkin become "Cannon" and 
Macedonsky 
"Mac" to finish it faster?]. Any way, the Russian American girl became a National Honor Society Scholar before most of "pure Americans" in her class, completed an AP program, which many of them from "really well-doing" families "don't really need to get into almost any Ivy", lead MIHS International Club, took Chemistry courses at UW, volunteered for its Medical Center, photo-documented medi
cinal flora of the Pacific Northwest, and even 
dosed caffeine for 
Starbucks to pay for her yoga class
. But 
still, "such a 
hard working student, 
broadly educated, multilingual, open-minded" and so on outstanding girl has not been selected for the Duke's pre-med program. 
At the 'Great Recession' times, h
er interviewer, an emancipated woman by the way, still conservatively picked-up a Jr of one wealthy Mr. apparently conducting profitable bailoutable financial operations via a to-large-to-brake bank and a bit smaller bank creating fake accounts in the King County of Spectacular Real Estate Mortgage Bubble, after agreeing with Tamara on every discussed issue, including "the importance of providing equal opportunities to equally deserving girls without private universities-attracting parents' assets in the country of vanishing dreams, where a few family clans are taking in turn the White House to keep the <1% making more than >99%..."

Finally disillusioned-about-America, the young lady responded 'in-kind'. She turned down all 'second choice' a.k.a. 'plan B' admission offers from less-top colleges with pre-med programs over-filled with JRs of wealthy practitioners of medicine and of additional, magically even less-taxable, arts; accepted an admission offer from the UW Honors Program; earned B.S. in Biology/Physiology from the Public Ivy; worked for a year as a tech at UW Genenic Sciences under the legendary Professor Benjamin Hall
; and then took a Research Scientist position in the Mullins Molecular Retrovirology Lab at UW Medicine to help 
fight human immuno-deficiency, among other human deficiencies...

Now independent Tamara Andreevna independently decides whether she should next A
try to get there or to a less-googled source of advanced education and guys breaking through anything on - an 
even from - Earth without any a$$istance from anyone like experience a joy of contributing
to a Breakthrough that brings up the cure to at least some of so many incurable worldwide; C) bring down to his left knee a guy who is ready to die for her smile [like this one?]; D) walk with "such a noble" man down the aisle to Ruslan and Lyudmila like Tsarevna, not
like count-less "princesses" sold on TV and social media panels, and
recess like Tsaritsa under Solemn March at
or at least in 
a place like this one; and E) give birth to one - and soon another - grey- and blue-eyed, meaning-fully named ........ and ......... That should be enough to bring her "creator", an old-fashion man apparently questioning "Man = Woman" Axiom, 
to his knees [that sounds like 'A' Plan!]

[No 'Hobbies' Section ending this contemporary Bio-blogging going out of Editor's control?] Try this Draft:
For a little fun,
 Mlle Tamara a) cycles daily till her
is needed; b) makes weekly a gallon of healthy soups from
natural ingredients before they're totally 
eradicated by Monsanto [now officially under Bayer, a chemicals producer]; c) cuisine monthly
to taste something tasteful without leaving the States of Fast GMO Food and 
hyper-overpriced, while 
bad, yet federally approved drugs; d) less often and on empty stomach only, meets with American Presidential Candidates surrounded by their incurably naive crowds, overrated speech writers, false poll producers, biased report producers, corrupt corporate news commentators, and additional mass media clowns, altogether re-playing "Gen[erational] Connection", "Age Category", "Racial Segregation", "Sexual Orientation", "Religious Belief", and ultimately - once again - "Russians are Coming", re-newed 'Panophobia' Game's still-all-old-and-dirty cards in billion$-wasting endless GeoPolitical Epopee, which most recently culminated in the American TV News Series "Trumped: The Drama Version Targeting Mostly Single, Promiscuous, via-Apple-iPhone-controlled, Gen Y Idiotesses", which began at this "Democratic West's Educational Arena" originally built and then renovated to make all Players-sponsoring money out of largely dark-colored "American gladiators"; and [are you ready for an even longer last point?] e) more and more often hikes further and further away from the increasingly and dangerously Ununited States of re-united Oligarchs [i.e. olygarchs of every, R/G/B primary, plus secondary, or minor, a.k.a. "Rainbow" Lovers including especially open-minded, also-the-usual-majority-of-humanity-putting-at-risk-with-their-specific-viruses Brothers, Sisters and Trans-Socially-Fashionable] exclusively profiting from natural and synthesized compounds over-drugged, on-mobile porn-addicted, thoroughly brain-sterilized
, para-militarily policed while closely-monitored, profitably racio-genetically profiled, and otherwise, ideally technologically(IT)-abused masses. Tamara The Intelligent stays away from any of them, with a few bottles of the purest 
Kona Nigari and Japanese DSLR
in place of renamed diabetogenic American drinks and re-ingeneered to be bath-wather-proof iphony
recorders-translators-transmitters of words, fingerprints and faces [not feces, yet, which is by the way an over-looked investment opportunity to launch another global gov.net.org led by next-generation conglomerated, 'from top .edu', dropouts], ideally carried
by a >8 cm-taller, BMI~18.8, traditionally [professionally] educated gentleman with a greater sense of humor and a multilingual, satiric and otherwise perfectly-heathy-individum's tongue [not this kind guy], who's capable to make even her, the next Sport Illustrating Model [photo-featured below] pause
 
and smile like no other girl under the Sun can,
 

before having Fun under Ven
us and Mars, as imaged par la grâce de l'exemple 
par les professionnels sans limit
 


 

                                

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